Understanding how a key antibody targets cancer cells

Important molecular insights for designing improved cancer therapies.

Scientists tackle indoor air pollution

Filtering out pollutants from indoor air is very important for the health of Canadians - as we spend up to 90% of our time indoors.

Dairy discovery could improve dialysis design for kidney failure patients

Researchers with USask Engineering were able to view an industrial milk-filtering #membrane in a way not seen before using our BMIT beamline

Analyzing antibodies

Researchers from the University of Toronto have developed antibodies that can neutralize COVID-19.

Developing antiviral drugs to treat COVID-19 infections

Using the CLS, researchers have isolated some promising inhibitors that could be used to treat COVID-19 infections.

Scientists break record while battling antibiotic resistance

Researchers from McGill University used the CLS to determine the physical structure of largest complex ever measured using the CMCF beamline.

The future of stroke treatment

A team of international collaborators has been researching a promising new therapeutic for the treatment of strokes and other brain injuries.

Using light to help combat Parkinson’s disease | Video

Over 100,000 Canadians are living with Parkinson’s disease. McGill researchers are using the Canadian Light Source to help search for potential drug targets for the disease.

Investigating the long-term health impacts of COVID-19 | Video

Dr. Jake Pushie is using the CLS and VIDO to study the virus that causes COVID-19 and its effects on blood vessels.

Fighting antibiotic resistance

Researchers report new insights into how a class of antibiotics commonly used in both medicine and agriculture are rendered useless by resistant germs.

Battling bad bugs

University of Guelph scientists fight antibiotic resistance by using our synchrotron to study scab disease in potatoes.

Cleaning pathogens from the air | Video

University of Saskatchewan scientists have designed an air sanitizing device that could help protect us from airborne pathogens like the ones that cause COVID-19 and the common flu.

CO2 and increased immunity | Video

Dr. Dustin King with Simon Fraser University and colleagues are using our CMCF beamlines to get a better understanding of how CO2 could be controlled to improve our immunity.

Helping stroke patients | Video

Dr. Jake Pushie's team at the University of Saskatchewan is examining risk factors for bleeding in the brain after stroke.

Analyzing a detergent to help allergy sufferers | Video

Ecologik, a Saskatoon-based company, used our CMCF beamline to analyze their dishwasher detergent to ensure there were no unknown contaminants in their product.

Improving heart disease outcomes for all patients

McGill researchers used the CLS to get one step closer to understanding the origins of arterial calcification, a process that contributes to heart disease.

Scientists discover potential method to starve the bacteria that cause Tuberculosis

By deepening our understanding of how Tuberculosis bacteria feed themselves, University of Guelph researchers have identified a potential target for drug treatment.

Extending the lifespan of N95 masks

Researchers are working to better understand how decontamination procedures might affect the structure and potential reuse of N95 masks.

Get out your vacuum: Scientists find harmful chemicals in household dust

A team of researchers from the CLS and Memorial University set out to determine whether bromine could be found in household dust.

In search of the perfect system

Streptavidin and biotin form a strong bond invaluable for many biotechnological applications. Researchers have taken a new approach to improve these widely used biotechnology tools.

Studying how to damage the COVID-19 virus

A University of Nevada researcher is using our Mid-IR beamline to study how nucleic acids get damaged under X-ray irradiation.

Water contaminant could have neurotoxic effects on children

Are those relying on private well water potentially at greater risk? Manganese isn’t considered a major water contaminant in America, but a new study is taking a closer look at whether it should be.

Stopping infection in its tracks

University of Calgary researchers developing therapeutics for COVID-19

Finding new therapies

Dr. Jiang Yin is using the CLS to find new therapies that will help treat COVID-19.

How cellular proteins control cancer spread

A new insight into cell signals that control cancer growth and migration could help in the search for effective anti-cancer drugs, according to McGill University researchers who used the CLS.

Promising new drug carrier could improve bone repair and cancer treatments

Western University and Shanghai Institute of Ceramics researchers used the CLS to explore a promising drug carrier that could be used to deliver cancer treatments and therapeutics for severe injuries.

Helping our immune systems bypass antibiotic resistance

As the search continues for new antibiotics to treat drug-resistant infections, researchers used the CLS to try to weaken the ability of bacteria to develop resistance in the first place.

Discovery could lead to stronger dental fillings … and less time at the dentist

Researchers used the CLS to discover how to create stronger dental fillings. This is great news for the 96% of Canadians who will have to contend with at least one cavity during their adult lives.

Developing microbeam radiation therapy for inoperable cancer

An innovative radiation treatment that could one day be a valuable addition to conventional radiation therapy for inoperable brain and spinal tumors is a step closer, thanks to new research led by researchers at the CLS.

Preventing hospital-acquired pneumonia

Researchers used the CLS to identify a previously unrecognized family of enzymes that put us at risk for deadly diseases.

Visualizing the bionanomachines that create potent antibiotics and other modern drugs

Researchers from McGill University and Yale University used the CLS to make a discovery that could help design future therapeutic drugs.

Discovery shows men and women develop heart disease differently

Scientists from McGill University used the CLS to uncover that different minerals block heart valves in men versus women. This discovery could impact how heart disease is diagnosed and treated for the different sexes.

Diabetes discovery challenges known research

A discovery by an international group of scientists challenges known research on diabetes and may open the door to new therapeutic approaches for the disease that affects nearly 500 million people globally.

Filtering for crystal-clear water anywhere in the world

Researchers use Canadian Light Source to advance the quest for an easy, inexpensive and effective filtration system that can be used in underdeveloped and remote areas of the world.

Targeting a deadly childhood winter illness

CLS helps biopharmaceutical company Merck to make a vaccine breakthrough for Respiratory Syncytial Virus (RSV), a virus that is one of the leading causes of hospitalization in babies.

Finding the right puzzle piece to stop cancer growth

McGill researchers use the CLS to analyze a new class of compounds that could help develop novel therapies for age-related cancers.

Unlocking the door to potential therapeutic treatments for serious complications from infections

Scientists used the CLS to solve the structure of an enzyme that could help burn victims and prevent deaths from different kinds of infections.

New understanding of antibiotic synthesis

Researchers have made great strides in understanding the functioning of enzymes that play and integral role in the production of antibiotics and other therapeutics.

Analyzing poppies to make better drugs

A team of researchers from the University of Calgary has uncovered new information about a class of plant enzymes that could have implications for the pharmaceutical industry.

A new generation of anti-malarial drugs

An international research team used the CLS to help determine the atomic structure of a protein kinase in parasites that cause malaria, which could help create a new generation of anti-malarial drugs.

The future of fighting infections

Researchers used the CLS to study proteins that a pathogen uses to break down sugar chains (glycans) present in human tissue during infections. This could lead to new treatments approaches for the bacterium.

Preventing heart attacks

Scientists from Quebec take an important step towards finding a potential cure for the disease that causes some strokes and heart attacks.

Preventing colorectal cancer and stillbirths

Researchers from the University of British Columbia used the Canadian Light Source to study a protein that could help prevent colorectal cancer and stillbirths.

Revolutionary discovery in leukemia research

Leukemia affects over 6,000 Canadians per year. A team of researchers used the Canadian Light Source to discover a new way to kill leukemia cancer cells.

Fighting antibiotic resistance

Researchers from the Universities of Guelph and Alberta used the CLS to identify a possible target in the prevention and treatment of bacterial infections.

Helping people to hear

Using advanced techniques at the CLS, scientists have created three-dimensional images of the complex interior anatomy of the human ear, which is key to improving the design of hearing implants.

Scientists make breakthrough in creating universal blood type

Researchers from University of British Columbia have made a breakthrough in their technique for converting A and B type blood into universal O, the type that is most needed by blood services.

Helping to shrink cancer tumours

Guided by “blueprints” produced at the CLS, scientists made structural changes to an antibody that is now showing a lot of potential for reducing cancer tumours.

Stress can lead to heart failure

Scientists have shown that heart arrhythmia can be acquired by people who are stressed out even if they have no genetic predisposition. This condition serves as a warning signal for atrial fibrillation and potential heart failure. The good news is that these researchers may have also discovered a potential therapy.

A potential therapy for treatment-resistant depression

There is a potential therapy on the horizon for people suffering from treatment-resistant depression thanks to a small biotech firm’s discovery of a molecule linked to cell function in the brain.

USask discovery may help improve cystic fibrosis treatment

A University of Saskatchewan medical research team has made a groundbreaking finding with potential to lead to more effective treatments for cystic fibrosis (CF).

Arrhythmia mutations in key proteins that oversees cellular functions crucial to health and survival

Researchers used the CLS to help understand the protein responsible for regulating heartbeats.

New research helps pursuit for malaria vaccine

Using the CLS, SickKids scientists have taken an important step forward on the path to finding effective biomedical interventions to halt the spread of malaria.

A new approach for finding Alzheimer's treatments

Researchers from McMaster University have found a new way to look for Alzheimer’s treatments, a disease that affects over 747,000 Canadians.

Researchers provide new insight into fate of Franklin Expedition

Using the CLS, a team of researchers were able to discover what happened to the crew of the Franklin Expedition of 1845.

Engineering 3D bio-printed scaffolds to help regenerate damaged peripheral nervous system

University of Saskatchewan researchers have looked at how we can use 3D printing to help damaged nervous systems to regrow.

Scientists make important discovery around antibiotic resistance

Researchers have discovered why superbugs are resistant to certain antibiotics.

Diagnosing osteoarthritis before it appears

Researchers from the University of Alberta and the University of Saskatchewan have identified early signs of bone disease using the CLS synchrotron.

Blocking African Sleeping Sickness' Tiny Culprit

A team of scientist have suggested an improved way to target and treat sleeping sickness while causing minimal harm to human hosts.

Building a better whooping cough vaccine

Breaking down whooping cough infections

A New Take on Tackling Malaria

According to the World Health Organization, one child dies from malaria every minute. New methods to combat malaria parasites are particularly important as these parasites continue to develop resistance to front-line drugs.