Friday, June 16, 2006 (Full Day Workshop)
Protein crystallography (PX) is a powerful technique for solving biological
problems at the molecular level. It increases our understanding of the structural
basis of basic biological and biochemical principles and is essential to
the design and optimization of ligands that bind to macromolecules in the
pharmaceutical industry.
This workshop will focus on both communicating recent research results and
discussing techniques of beamline development, data collection, processing,
solving structures and user access, including applications at the CLS protein
crystallography beamline. Additionally there will be presentations demonstrating
the synergistic advantages of combining PX and SAXS in approaching biological
problems.
Workshop Organizer: Pawel Grochulski, Canadian Light Source
Inc.
Location: Arts 134
Time |
Speaker |
Affiliation |
Title |
| 8:00-16:30 |
Registration Geology Atrium |
8:30 |
Opening Remarks and Introduction to CMCF (Pawel
Grochulski, CLS) |
8:40 |
Paul Adams |
Advanced Light Source, Lawrence Berkeley National Laboratory |
Automated structure determination with
PHENIX |
9:20 |
Mirek Cygler |
Biotechnology Research Institute, National Research Council of
Canada |
Structural Characterization of E.
coli Histidine Synthesis Pathway |
10:00 |
Coffee Break Geology Atrium |
10:30 |
Robert Fischetti |
Advanced Photon Source, Argonne National Laboratory |
GM/CA Canted Undulator Beamlines for
Macromolecular Crystallography: Design and Performance |
11:10 |
Andrzej Joachimiak |
Advanced Photon Source, Argonne National Laboratory |
Structural Genomics
combines genomic data and structural biology to advance protein fold
and function space |
11:50 |
Andrzej Joachimiak |
Advanced Photon Source, Argonne National Laboratory |
The Structural
Biology Center beamlines at the Advanced Photon Source |
12:20 |
Lunch Geology Atrium |
13:40 |
Yu Luo |
Department of Biochemistry, University of Saskatchewan |
Novel insight from crystallographic studies
on an archaeal RadA recombinase |
14:20 |
Bhushan Nagar |
Department of Biochemistry, McGill University |
Structural basis for the autoinhibition
and activation of c-Abl tyrosine kinase |
15:00 |
Coffee Break Geology Atrium |
15:30 |
Scott Williams |
Department of Chemistry, The Scripps Research Institute |
Assembled Structure of the Mre11/Rad50/DNA
complex from X-ray Solution Scattering and Crystallography |
16:10 |
Jurgen Sygusch |
Department of Biochemistry, Université de Montréal |
Cryotrapping of reaction intermediates – structural
exploration of catalysis |
16:50 |
Workshop Adjournment |
Program Related Inquiries to: Pawel Grochulski pawel.grochulski@lightsource.ca
This workshop was organized and sponsored by the Canadian
Light Source and the Canadian Federation of Biological Societies.
Support for this workshop is provided in part by the
Saskatchewan Health Research
Foundation and the Molecular
Design Research Group.
Last modified: 2009-04-22 11:04:30
