Synchrotron Protein Crystallography
Friday, June 16, 2006 (Full Day Workshop)
Protein crystallography (PX) is a powerful technique for solving biological problems at the molecular level. It increases our understanding of the structural basis of basic biological and biochemical principles and is essential to the design and optimization of ligands that bind to macromolecules in the pharmaceutical industry.
This workshop will focus on both communicating recent research results and discussing techniques of beamline development, data collection, processing, solving structures and user access, including applications at the CLS protein crystallography beamline. Additionally there will be presentations demonstrating the synergistic advantages of combining PX and SAXS in approaching biological problems.
Workshop Organizer: Pawel Grochulski, Canadian Light Source Inc.
Location: Arts 134
Time |
Speaker |
Affiliation |
Title |
|---|---|---|---|
| 8:00-16:30 | Registration Geology Atrium | ||
8:30 |
Opening Remarks and Introduction to CMCF (Pawel Grochulski, CLS) |
||
8:40 |
Paul Adams |
Advanced Light Source, Lawrence Berkeley National Laboratory |
|
9:20 |
Mirek Cygler |
Biotechnology Research Institute, National Research Council of Canada |
Structural Characterization of E. coli Histidine Synthesis Pathway |
10:00 |
Coffee Break Geology Atrium |
||
10:30 |
Robert Fischetti |
Advanced Photon Source, Argonne National Laboratory |
GM/CA Canted Undulator Beamlines for Macromolecular Crystallography: Design and Performance |
11:10 |
Andrzej Joachimiak |
Advanced Photon Source, Argonne National Laboratory |
|
11:50 |
Andrzej Joachimiak |
Advanced Photon Source, Argonne National Laboratory |
The Structural Biology Center beamlines at the Advanced Photon Source |
12:20 |
Lunch Geology Atrium |
||
13:40 |
Yu Luo |
Department of Biochemistry, University of Saskatchewan |
Novel insight from crystallographic studies on an archaeal RadA recombinase |
14:20 |
Bhushan Nagar |
Department of Biochemistry, McGill University |
Structural basis for the autoinhibition and activation of c-Abl tyrosine kinase |
15:00 |
Coffee Break Geology Atrium |
||
15:30 |
Scott Williams |
Department of Chemistry, The Scripps Research Institute |
|
16:10 |
Jurgen Sygusch |
Department of Biochemistry, Université de Montréal |
Cryotrapping of reaction intermediates – structural exploration of catalysis |
16:50 |
Workshop Adjournment |
||
Program Related Inquiries to: Pawel Grochulski pawel.grochulski@lightsource.ca
This workshop was organized and sponsored by the Canadian Light Source and the Canadian Federation of Biological Societies.
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Support for this workshop is provided in part by the
Saskatchewan Health Research
Foundation and the Molecular
Design Research Group.
Last modified: 2012-01-19 17:01:37