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Newsletter============================================CLS E-News Vol. 6 No. 3 October 30, 2008 www.lightsource.ca University of Saskatchewan, Canada ============================================
********************************************** 1. JOSEF’S JOURNAL On behalf of the CLS Board of Directors, I would like to welcome the following new members to the Board:
I was pleased to meet these new members and the rest of the Board during my first Board retreat as Executive Director on October 2. The next meeting of the Board will be held on December 4. Meetings scheduled for 2009 include February 26, June 23 and October 1, with a Board retreat December 3. More information about the Board and its current membership can be found on the CLS website at: Stay tuned for more announcements in the next issue. ************************************************ 2. 2008 ACTIVITY REPORT: CALL FOR SUBMISSIONS The Canadian Light Source Activity Report communicates the exciting research and development activity of Canada’s national synchrotron facility to the wider scientific community. This edition of the CLS Activity Report summarizes the progress made at the CLS in the areas of scientific research and facility development and operations from January 1 to December 31, 2008. The key to a successful report is input from our users. All users who conducted research at the CLS during 2008 are invited to submit a short article for the science section of the report. Users wishing to contribute an article should e-mail the editor at the above contact with their intent to submit by Monday, December 15, 2008. Further information, including submission guidelines and templates are available at http://www.lightsource.ca/uso/activity_report.php. The deadline for submissions is January 26, 2009. ************************************************ 3. SCIENCE HIGHLIGHT: EXPRESSION, PURIFICATION AND PRELIMINARY CRYSTALLOGRAPHIC ANALYSIS OF N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLYLTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS The gene product of open reading frame Rv1018c from Mycobacterium tuberculosis is annotated as encoding a probable N-acetylgucosamine 1-phosphate uridylyltransferase (MtbGlmU), an enzyme that catalyzes the biosynthesis of UDP-N-acetylglucosamine, a precursor common to lipopolysaccharide and peptidoglycan biosynthesis. Following overexpression in Escherichia coli, the enzyme was purified and crystallized using the hanging-drop vapour-diffusion method. Native diffraction data were collected from crystals belonging to space group R32 and processed to a resolution of 2.2 angstroms. Yin, J., Garen, C.R., Cherney, M.M., Cherney, L.T., James, M.N.G. (2008) Acta Crystallographica, F64, 805-808. DOI: 10.1107/S1744309108024500 ************************************************ The Users Advisory Committee met in Saskatoon on October 20 for a day-long retreat with Josef Hormes. In attendance were: Josef Hormes, CLS; Serge Desgreniers, University of Ottawa; Grant Henderson, University of Toronto; Farideh Jalilehvand, University of Calgary; Pierre Kennepohl, UBC; Stewart McIntyre UWO; Dennis Tokaryk UNB; and Graham George, Ramiswami Sammynaiken, Brian Bewer, Derek Peak, and Helen Nichol, U. of S. Ernst Bergmann (U. of A.) was unable to attend but provided some information via e-mail. Discussions focused on improving the CLS user experience as it pertains to software, the CLS website, proposals, onsite amenities, travel, and beamline commissioning. 5. CLS USER FEATURED IN CIHR ANNUAL REPORT The research of Dr. Helen Nichol, an associate professor at the University of Saskatchewan and Chair of the CLS Users’ Advisory Committee, is featured in the 2007-08 Annual Report of the Canadian Institutes of Health Research (CIHR). Dr. Nichol’s investigation into the causes of neurodegenerative diseases using synchrotron radiation is one compelling example of the science conducted at the CLS, of which CIHR is a funding partner. The CIHR 2007-2008 Annual Report, “Portraits in Partnerships” is available for download from the CIHR website at http://www.cihr-irsc.gc.ca/e/documents/cihr_annual_report_2007-08_e.pdf. ************************************************ 6. NOW HIRING – SCIENCE AND RESEARCH ASSOCIATES We are currently accepting applications for the following positions:
For the full position descriptions please go to: http://www.lightsource.ca/careers =============================================== Last modified: 2008-11-03 10:11:13 |
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